This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science. Table of Contents Preface. Introduction. Biochemical Data: Analysis and Management. Biochemical Exploration: Internet Resources. Molecular Graphics: Visualization of Biomolecules. Biochemical Compounds: Structure and Analysis. Dynamic Biochemistry: Biomolecular Interactions. Dynamic Biochemistry: Enzyme Kinetics. Dynamic Biochemistry: Metabolic Simulation. Genomics: Nucleotide Sequences and Recombinant DNA. Genomics: Gene Identification. Proteomics: Protein Sequence Analysis. Proteomics: Prediction of Protein Structures. Phylogenetic Analysis. Molecular Modeling: Molecular Mechanics. Molecular Modeling: Protein Modeling. Appendix 1: List of Software Programs. Appendix 2: List of World Wide Web Servers. Appendix 3: Abbreviations. Index.