The Python-Based Laboratory can be used as a textbook for science and engineering instructional laboratory students who are being taught up-to-date Python-based experimental skills. The book also works well as a self-study guide for professional laboratory researchers, industrial engineers, hobbyists, and electronics enthusiasts seeking to automate tasks using Python. Topics covered include the control of data acquisition devices (including multifunction data acquisition hardware and IEEE-interfaced stand-alone instruments), data file storage and presentation, digitized data concepts (such as resolution, sampling frequency, and aliasing), and data analysis techniques (curve fitting and fast Fourier transform). As readers work their way through the book, they build several computer-based instruments, including a DC voltmeter, digital oscilloscope, DC voltage source, waveform generator, blinking LED array, digital thermometer, and spectrum analyzer. Each chapter concludes with a Do-It-Yourself project and a Use It! example as well as a healthy selection of homework-style problems, allowing readers to test their understanding and further develop their Python-based experimentation skills.