Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

Few scientists have the multidisciplinary experience needed to control all aspects of a high-throughput screening (HTS) drug discovery project. This volume integrates the knowledge of experts in biology, chemistry, informatics, instrumentation, automation, technology development, and project management. Enabling researchers in industrial and academic settings to find the most efficient way to carry a project from start to finish, this volume identifies critical targets that are of relevance to drug discovery, discusses the components of the HTS process, and provides step-by-step instructions for an HTS project, while also examining emerging technologies and systems.