Growth Factors and Wound Healing

I. General Concepts.- 1. An Overview of Wound Healing Biology.- 2. Growth Factors and Angiogenesis in Wound Healing.- 3. The Regulation of Basic Fibroblast Growth Factor (FGF-2) Through Limited Bioavailability.- 4. Cultured Skin Cells for Wound Closure and for Promoting Wound Healing.- 5. The Growth Hormone Insulin-Like Growth Factor-I Axis.- II. Role of Nutrients in Wound Healing Responses.- 6. Use of Exogenous Amino Acids in Wound Healing.- 7. Vitamin A-Growth Factor Interactions in Wound Healing.- 8. Interactions Between Nutrients and Growth Factors in Cellular Anabolism and Tissue Repair.- III. Endogenous Growth Factors and Wound Healing.- 9. Fibroblast Growth Factor Receptors.- 10. Arginine and Nitric Oxide (NO) Interactions in the Healing Wound.- 11. Endogenous Growth Factors and Nutrients in the Healing Wound.- 12. Epidermal Growth Factor in Wound Healing: A Model for the Molecular Pathogenesis of Chronic Wounds.- IV. Clinical Application of Growth Hormone and IGF-I Therapy.- 13. Growth Hormone Therapy in Human Burn Injury.- 14. Effects of Exogenous Growth Hormone in Postoperative Immune Function and Other Clinical Outcomes.- 15. Effect of Growth Hormone Administration on Colonic Healing and Repair.- 16. Modulation of IGF-I Therapy by IGFBP-3: Potential Utility in Wound Healing.- V. Clinical Application of Peptide Growth Factors.- 17. Roles of Keratinocyte Growth Factor in Epithelial Growth and Regeneration.- 18. Hepatocyte Growth Factor.- 19. The Biology of Vascular Endothelial Growth Factor, a Specific Regulator of Angiogenesis.- 20. FDA Regulatory Concerns for Wound Healing Biologics.- Author Index.