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Advances in Parasitology: Volume 132

Advances in Parasitology: Volume 132

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The discipline of parasitology is undergoing a profound paradigm shift as anthropogenic pressures dissolve the boundaries separating wildlife, domestic animals, and human populations. This Volume brings together three foundational chapters on vector-borne parasite transmission, wildlife reservoirs, and the ecological frameworks necessary to combat global zoonoses. In the opening Chapter, Sarah N. Farrell and colleagues propose that treating the mosquito vector rather than the human host with antimalarial compounds may represent a suitable and sustainable strategy for malaria control. By attacking the Plasmodium parasite at its bottleneck oocyst stage within the vector, this approach exploits a lower parasite population size to drastically minimize the evolutionary selection pressure for drug resistance. Transitioning from micro-level vector dynamics to macro-level landscape epidemiology, Andrea Springer and colleagues document how conservation successes and urban adaptation have shifted the distribution of zoonotic pathogens. Focusing on the red fox as primary sentinel, the authors illustrate how wild reservoirs dynamically interact with domestic animals and humans, highlighting the importance of the health triangle connecting wild carnivores to urban public health. Finally, Alicia Rojas and Alberto Solano-Barquero dissect the micro- and macroevolutionary events, such as host-switching and hybridization, that allow multi-host parasites to overcome human physiological defenses, and propose instead a balanced "One Health pentad" that gives equal weight to wildlife reservoirs, intermediate bridge hosts, vectors, and complex environmental stages.

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Pub dateJul 16, 2026
ISBN-100443470642
ISBN-139780443470646
LanguageEnglish
Last updated 2026-07-25 20:18
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Helminths include one of the most diverse and geographically widespread groups of parasites which infect humans and animals. About 100 species have been reported from humans, usually producing asymptomatic infection or mild symptoms. However, about 20 species are of public health importance causing severe or even fatal infections. In many parts of Africa parasitic helminths are responsible for enormous economic losses, hampering rural development programmes and reducing the pace of economic growth. Many parasitic helminths are either zoonoses (diseases naturally transmitted between vertebrate animals and man) or have evolved from animal parasites. The modification of the environment through wars, famine and the ever expanding and increasingly mobile human population brings people into close contact with new environments and wildlife species which makes the study and control of zoonoses of special interest and complexity. In Africa, the transmission of helminth parasites is highly influenced by the ever changing social and cultural differences between diverse groups of peoples and their interaction with wild and domestic animals. It is not surprising, therefore, that approaches to the study and control of parasitic zoonoses require intersectoral cooperation between physicians, veterinarians, parasitologists, zoologists, demographers, anthropologists, engineers and economists to provide the breadth of knowledge and expertise required to develop our understanding of these diseases and to devise methods for their control. This book provides a selective compilation of parasitic helminths, many of which are zoonoses which create important economic and public health problems in Africa.
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