Quantitative Radiobiology for Proton Therapy

This book is an extension and major update of the author's previous work, titled, "Practical Radiobiology for Proton Therapy Planning" (IOP 2018). The book describes the relative biological effectiveness (RBE) issues within proton therapy and advises on how to use a variable RBE within treatment planning and in dose prescription to improve the safety of proton and other forms on ion beam therapy. Decision-making advice is also provided for protocol breaches, retreatments, dose rate effects and risk assessment. This book is intended for those who already have basic knowledge of radiotherapy and radiobiology, although there is guidance through the fundamental principles for those who are 'discipline crossing'.

Key Features

• Provides coverage of key topics such as blood oxygen saturation, tissue oxygenation and respiration assessment.
• An extension and major update to "Practical Radiobiology for Proton Therapy Planning" by the author (IOP 2018).
• Brings thorough updates to each chapter, with the inclusion of more quantitative methods where appropriate.
• Contains end-of-chapter summaries; chapter problems; and simple experiments with pulse oximeters if the device is available.
• Includes Mathematica codes where appropriate.