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Group Sequential Methods with Applications to Clinical Trials

Group Sequential Methods with Applications to Clinical Trials

No customer reviews yet ISBN 9780849303166 Chapman and Hall/CRC

This book describes group sequential stopping rules designed to reduce average study length and control Type I and Type II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Group Sequential Methods with Applications to Clinical Trials effectively surveys and extends modern methods for planning and conducting interim analyses.

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BrandChapman and Hall/CRC
Pub dateSep 15, 1999
ISBN-100849303168
ISBN-139780849303166
Hardcover410.0 pages
LanguageEnglish
Dimensions9.21 × 1.12 × 6.14 in
Weight2 lb
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