Experimental Models of Diabetes

Internationally renowned experts describe the models, provide data obtained with those models, and discuss the relative usefulness of models in relation to the diabetic syndrome in humans. It examines the most widely used model, the streptozotocin (STZ) rat, condensing a massive quantity of literature to present both the general effects of STZ diabetes and the effects on individual organ systems. It also discusses more recent diabetic models, such as the BB rat, the NOD mouse and Zucker and Zucker Diabetic Fatty rat models and examines genetic models of insulin dependent diabetes mellitus (IDDM) and compares them to chemically induced IDDM models.