Biopharmaceuticals in Plants: Toward the Next Century of Medicine

Designed as a basic multidisciplinary reference for researchers, this book discusses plant transformation techniques, generation of transgenic plants, engineering of plant viruses to produce vaccine proteins or peptides, risk analysis, and future applications. It addresses the basis of mucosal immunity using plant-based oral vaccines, organelle targeting for vaccine production, and the role of glycosylation in plant-made mammalian proteins. It also considers vaccine production in entire crops or in large batch cell suspension cultures as well as the construction of clinical trials.