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Home/ Molecular Neurosurgery with Targeted Toxins (2005)
Molecular Neurosurgery with Targeted Toxins (2005)

Molecular Neurosurgery with Targeted Toxins (2005)

No customer reviews yet ISBN 9781588291998

Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail too give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.

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Pub dateMar 22, 2005
ISBN-101588291995
ISBN-139781588291998
LanguageEnglish
Last updated 2026-03-13 00:47
$208.19
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