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Oligonucleotide Synthesis Methods and Applications Methods in Molecular Biology 288
by Oligonucleotide Synthesis: Methods and Applications (2005)
$204.15
Description
A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.
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Product Details
- Humana Brand
- Sep 1, 2004 Pub Date:
- 9781588292339 ISBN-13:
- 1588292339 ISBN-10:
- 452.0 pages Hardcover
- English Language
- 9 in * 1.25 in * 6.25 in Dimensions:
- 2 lb Weight:
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