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Leading experts explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke. The authors relate changes in gene expression to physiological endpoints-such as functional imaging paradigms-to produce a more holistic approach in which molecular biology goes hand-in-hand with stroke pathophysiology. The book shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke as well as rapid development of the next generation of stroke therapeutics.