DiEugenio updates all of the topics that he introduced in 1992 with the first edition of Destiny Betrayed. He has used the declassification process of the Assassination Records Review Board (ARRB) to gain the most current and accurate information on subjects including Clay Shaw and the Garrison investigation; US-Cuban policy from 1957 to 1963; the newly exposed mistaken beliefs of the Warren Commission; Kennedy's challenge to the Cold War consensus in 1961 and where he came up with that challenge; and more. The author primarily emphasizes the New Orleans aspects of the Kennedy murder investigation, the Garrison inquiry, and the new and secret data that strengthens Garrison's case.