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Non-cytotoxic activity of B. jararacussu venom

Non-cytotoxic activity of B. jararacussu venom

by Ruiz Rivero, José Vitelio
No customer reviews yet ISBN 9786206835516

Ophidian venoms are biological resources of important pharmacological value. In addition to the small number of antiviral drugs, numerous pathogens develop mechanisms to escape the action of drugs, resulting in increasing rates of resistance. Biomolecules contained in ophidian venoms have been shown to have high therapeutic value and could be used as antimicrobial agents. The aim of this work is to evaluate the non-cytotoxic activity of crude venom isolated from Bothrops jararacussu in peripheral blood mononuclear cells. In this study, mononuclear cells from healthy donors were separated. After activating the cells with phytohemagglutinin and interleukin-2, different concentrations of the venom were added to assess its non-cytotoxic activity. This study paves the way for new research aimed at identifying the antimicrobial activities of crude venoms and their fractions.

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Pub dateMay 8, 2025
ISBN-106206835510
ISBN-139786206835516
LanguageEnglish
Last updated 2026-09-03 17:50
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