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This book presents a rare and detailed case report of an intraosseous odontogenic keratocyst (OKC) occurring in the mandible of a 33 year old male patient. It explores the clinical presentation, radiographic findings, histopathological features, differential diagnoses, and the surgical management approach adopted. Emphasis is placed on the lesion's aggressive nature, high recurrence potential, and the importance of long-term follow-up. The report aims to enhance understanding among dental and medical professionals regarding this uncommon but significant jaw pathology.