DMSO Guide Made Easy for Beginners: Understanding the Science of DMSO

Understanding how DMSO (Dimethyl sulfoxide) works involves exploring its mechanisms of action, particularly in the context of its solvency and its ability to facilitate the transdermal absorption of various substances. DMSO's primary function, and one of its most well-known attributes, is its exceptional solvency. It can dissolve a wide range of organic and inorganic substances, making it a valuable solvent in various fields, including chemistry and biology.

DMSO is a highly polar compound, with a sulfur-oxygen double bond and the ability to form hydrogen bonds. This high polarity allows it to interact with a broad spectrum of compounds, including those that are both polar and nonpolar. As a result, DMSO can dissolve substances that might be insoluble in other common solvents like water. DMSO can act as a nucleophile, meaning it can donate electrons to react with electrophilic species. This property allows DMSO to participate in various chemical reactions, making it a valuable reagent in organic synthesis.
DMSO can effectively dissolve ionic compounds, creating a medium for various chemical reactions and processes, such as ion transport and electrolysis. DMSO is both hydrophilic (attracted to water) and lipophilic (attracted to lipids or fats). This dual nature contributes to its ability to dissolve a wide range of substances, including both hydrophilic and lipophilic molecules.

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